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Find out what scientists have discovered could be an important cause for Type 2 Diabetes that could make us rethink the way we approach treatment for this devastating disease.

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Original Article: Pancreatic Beta Cell Dedifferentiation as a Mechanism of Diabetic Beta Cell Failure.
Talchai et al. Cell, 2012. 150 (6) p. 1223-1234.

A University of Oregon graduate student’s discovery could someday lead to new treatments for the nearly 1.5 million Americans with Type 1 diabetes. The research, led by Jennifer Hampton Hill in the UO lab of biologist Karen Guillemin, was detailed in a paper published in the journal eLife on Dec. 13, 2016.

A professor in the UO’s Department of Biology and the Institute of Molecular Biology who also serves as director of the META Center for Systems Biology, Guillemin examines the role bacteria play in animal development and disease. She uses a research model she helped develop involving a special kind of sterile zebrafish that don’t have any internal or external microbes of their own — no microbiome, making them germ-free — so scientists can better determine the role those microbes play as animals grow.

Having studied the pancreas and its importance to metabolism, and knowing that host metabolism can be strongly influenced by microbes, Hampton Hill naturally developed an interest in the role of bacteria in pancreatic development, which Guillemin encouraged.

Read more at https://around.uoregon.edu/BefA
Paper link: https://elifesciences.org/articles/20145
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Dr. Krishna Patil is a Consultant Nephrologist, Hypertension Specialist and Transplant Physician in the Department of Nephrology at Sunshine Centre for Renal Sciences – Sunshine Hospitals, Hyderabad.
#KidneyDisease #KidneyDiseaseSymptoms #KidneyDiseaseDiet #KidneyDiseaseTreatment

Phosphorus is a mineral found in almost all foods. It works with calcium and vitamin D to keep your bones healthy. Healthy kidneys keep the right amount of phosphorus in your body. When your kidneys are not working well, phosphorus can build up in your blood. Too much phosphorus in your blood can lead to weak bones that break easily.

Many people with kidney disease need to limit phosphorus.

Depending on your stage of kidney disease, your doctor may also prescribe a medicine called a phosphate binder. This helps to keep phosphorus from building up in your blood. A phosphate binder can be helpful, but you will still need to watch how much phosphorus you eat. Ask your doctor if a phosphate binder is right for you.
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The Keto Diet and Kidney Function | A Kidney Doctor Explains | The Cooking Doc®

*This is not meant as medical advice, it is for informational purposes only. Please discuss any and all health concerns with your doctor

Read the full blog here: https://www.thecookingdoc.co/the-keto-diet-and-your-kidneys/

Dr. Blake is The Cooking Doc and a board certifice nephrologist, Kidney Doctor. His patients often ask him if the keto diet is safe for people with kidney disease. Here is his response.

New Book Available: The Cooking Doc’s Kidney-Healthy Cooking. E-book and paperback available for purchase here: https://www.thecookingdoc.co/kidney-healthy-cooking-book/

“With recipes that range from sweet to savory and will take you from appetizer to dessert, healthy cooking takes the main stage in The Cooking Doc’s Kidney-Healthy Cooking. This delightful cookbook is full of stunning photographs and lovely illustrations; valuable, practical information about kidney health, and tantalizing, tasty go-to recipes. It’s an absolute must have on your cookbook shelf. The Cooking Doc has done it – eating healthy never looked so good!”
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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. The purpose of this website is to promote health and wellness. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.
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Acute Pyelonephritis (Kidney Infection) | Causes, Pathophysiology, Signs & Symptoms, Diagnosis, Treatment

Acute pyelonephritis is a bacterial infection of the kidney that causes inflammation of the kidney. It is often a complication of a urinary tract infection, and most commonly occurs in young women.
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DKD, or diabetic nephropathy: pathophysiology, symptoms, risk factors, diagnosis and management. For patient education. This video is available for instant download licensing here: https://www.alilamedicalmedia.com/-/galleries/narrated-videos-by-topics/diabetes/-/medias/0079bcc6-2a8f-48d6-947d-57b464d2e271-diabetic-kidney-disease-narrated-animation
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All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Diabetic kidney disease, or diabetic nephropathy, is kidney disease caused by diabetes. It’s a very common diabetic complication, affecting about one third of people with diabetes type 1, and half of those with diabetes type 2. Diabetic kidney disease is responsible for most of the excess mortality associated with diabetes.
Because the kidneys remove metabolic wastes, control blood pH, regulate fluid and electrolyte balance, as well as produce several hormones; loss of kidney function results in accumulation of toxic wastes, electrolyte imbalances, and a number of other health problems.
The disease develops slowly over time, progressing from renal insufficiency to end-stage renal failure. Often, initial loss of renal tissue does not produce any symptoms. Symptoms typically appear when a significant portion of kidney function is already lost. The ability to concentrate urine is usually the first to be impaired, resulting in frequent trips to the bathroom, especially at night. Other early signs include fatigue, loss of appetite, and decreased mental ability.
Chronic high blood glucose levels, together with high blood pressure caused by diabetes, bring damage to tiny blood vessels in the kidneys, affecting their functions. Cellular degeneration in the functional units of the kidneys, the nephrons, in particular the podocytes of renal glomeruli, further contributes to the impairment of renal functions.
Diabetes, especially when poorly managed, is the biggest risk factor for chronic kidney disease. Other risk factors are the same as those for high blood pressure and include smoking, having high cholesterol levels, and being overweight.
Because initial loss of renal tissue does not produce any symptoms, it is important for diabetic patients to test annually for kidney functions. The tests typically include blood and urine analysis.
Prevention and management strategies consist of controlling blood sugar levels, blood pressure, and cholesterol levels; all of which can be achieved with a combination of lifestyle changes and medications.
Lifestyle measures typically include a healthy diet with low salt intake, increased physical activity, weight management, and smoking cessation.
Among all blood pressure lowering medications, ACE inhibitors and angiotensin receptor blockers, which block the renin–angiotensin–aldosterone system, work best to protect kidney functions.
End-stage kidney disease requires dialysis or kidney transplantation.
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Understand these 10 symptoms of kidney disease.

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*Emerging data from EMPA-KIDNEY study*
the content is not available for HCPs from UK and Ireland

Speaker:
Will Herrington, United Kingdom

Panellists:
Rikke Borg, Denmark
Katharina Schütt, Germany

Moderator:
Beatriz Fernandez Fernandez, Spain

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Nephrologist Dr. Sumeska Thavarajah talks about treatment options for end-stage renal disease, including a demonstration of various dialysis option. #RenalDisease #JohnsHopkins

Meet Dr. Thavarajah https://www.hopkinsmedicine.org/profiles/results/directory/profile/0018291/sumeska-thavarajah

Learn more https://www.hopkinsmedicine.org/nephrology/

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What are kidney stones, and how do they form? How do I know if I have kidney stones? Are they dangerous? Walter Mutter, M.D. Chief of Nephrology at Newton-Wellesley Hospital and Lecturer in Medicine at Harvard Medical School, discusses kidney stones, how to prevent them, and what you should do if you have them.

Subscribe Link: https://www.youtube.com/channel/UCYrLjATd88gPwIKntCoR0WQ?sub_confirmation=1

0:00 – Intro
0:15 – What Are Kidney Stones, How Do They Form?
0:49 – How Do I Know If I Have Kidney Stones?
1:34 – Do Genetics Play A Role?
1:55 – Are Kidney Stones Dangerous If Left Untreated?
2:20 – How Long Do They Take To Pass?
3:02 – How Do We Test For Kidney Stones?
4:00 – What Happens If I’m Pregnant And Have Kidney Stones?
4:23 – What Are The Causes Of Kidney Stones?
5:28 – What Can I Do To Prevent Kidney Stones?
6:33 – How Do I Prevent Them From Getting Worse?
7:25 – How Do We Remove Them?
8:09 – What’s The Worst Thing I Can Do If I Have Kidney Stones?
8:35 – What’s The Best Thing I Can Do About Kidney Stones?

About Mass General Brigham:
Mass General Brigham combines the strength of two world-class academic medical centers, five nationally ranked specialty hospitals, 11 community hospitals, and dozens of health centers. Our doctors and researchers accelerate medical breakthroughs and drive innovations in patient care. They are leaders in medical education, serving as Harvard Medical School faculty and training the next generation of physicians. Mass General Brigham’s mission is to deliver the best, affordable health care to patients everywhere. Together, we transform the health of our communities and beyond.

#KidneyStones #MGB #MassGeneralBrigham

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Kidney Stones: Causes, Symptoms, Treatment, and Prevention | Mass General Brigham

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